Thursday, January 15, 2026

All the Celebs Who’ve Opened Up About Using GLP-1s

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Amy Schumer

Although the comedian previously shared that she tried a GLP-1 but couldn’t tolerate the side effects, Schumer later told social media followers that she connected with Midi Health—a company she’s also invested in—to help treat her perimenopause symptoms. She said she was prescribed estrogen and progesterone and added that Mounjaro has been “great.”

Since then, Schumer has shared her weight loss and removed some older pre–weight-loss photos from Instagram, explaining that her focus has been on feeling better physically. “I have been working to be pain free and I finally am,” she wrote in a since-deleted post, adding that her endometriosis has improved, her back is healing and she no longer has Cushing syndrome.

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